2008 Chillicothe Football Schedule
| Date | Opponent | Time | |
| 0 | Fri, Aug 29, 08 | at Rule | 7:30 PM |
| 1 | Fri, Sep 5, 08 | vs Saint Jo | 7:30 PM |
| 2 | Fri, Sep 12, 08 | at Knox City | 7:30 PM |
| 3 | Fri, Sep 19, 08 | at Newcastle | 7:30 PM |
| 4 | Fri, Sep 26, 08 | at Wichita Falls Christian | 7:30 PM |
| 5 | BYE | ||
| 6 | Fri, Oct 10, 08 | vs Guthrie * | 7:30 PM |
| 7 | Fri, Oct 17, 08 | at Jayton * | 7:30 PM |
| 8 | Fri, Oct 24, 08 | vs Patton Springs * | 7:30 PM |
| 9 | Fri, Oct 31, 08 | at Benjamin * | 7:30 PM |
| 10 | Fri, Nov 7, 08 | vs Harrold * | 7:30 PM |